Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	102190
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Analysis of risk factors for bile leakage after laparoscopic exploration and primary suture of common bile duct
Manuscript Source	Unsolicited Manuscript
All Author List	Qing-Song Yang, Meng Zhang, Chang-Song Ma, Da Teng, Ao Li, Ji-Dong Dong, Xi-Fei Wang and Fu-Bao Liu
Funding Agency and Grant Number	Funding Agency Grant Number Wannan Medical College Teaching Hospital Special Application for Scientific Research No. WK2023JXYY036 Anhui Provincial Translational Clinical Medical Research Special Application No. 202204295107020062
Corresponding Author	Fu-Bao Liu, Chief Physician, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery, The First Affiliated Hospital of Anhui Medical University, No. 120 Wanshui Road, Nanqiao District, Hefei 230022, Anhui Province, China. 18955015210@163.com
Key Words	Laparoscopic common bile duct exploration; Primary duct closure; Bile leakage; Risk factor analysis; Cumulative summation
Core Tip	This study identifies key risk factors for bile leakage following laparoscopic common bile duct exploration and primary duct closure (PDC). Through retrospective analysis and logistic regression, fibrinous exudation and direct bilirubin/indirect bilirubin were found to be significant independent risk factors. The cumulative summation method demonstrated that a minimum of 51 cases is required for surgeons to master the PDC technique effectively. Proper assessment of duodenal papilla function, ensuring bile duct patency, and achieving surgical proficiency are essential for minimizing complications. Adhering to these guidelines may optimize patient outcomes and promote PDC as a preferred method in clinical practice.
Citation	<p>Yang QS, Zhang M, Ma CS, Teng D, Li A, Dong JD, Wang XF, Liu FB. Analysis of risk factors for bile leakage after laparoscopic exploration and primary suture of common bile duct. <i>World J Gastrointest Surg</i> 2025; 17(3): 102190</p>

Received	2024-10-23 10:20
Peer-Review Started	2024-10-23 10:20
To Make the First Decision
Return for Revision	2024-11-19 11:40
Revised	2024-12-23 11:12
Second Decision	2025-01-07 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-08 00:06
Articles in Press	2025-01-08 00:06
Publication Fee Transferred	2024-12-25 09:27
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-31 07:59

ISSN	1948-9366 (online)
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