Publication Name	World Journal of Methodology
Manuscript ID	102758
Country	Argentina

Category	Orthopedics
Manuscript Type	Retrospective Cohort Study
Article Title	Impact of depression on functional status in elderly patients undergoing total knee arthroplasty
Manuscript Source	Invited Manuscript
All Author List	Tomas Ignacio Nicolino, Maximiliano Smietniansky, Bruno Boietti, Ignacio Garcia-Mansilla, Lisandro Carbo and Cintia Belen Martinez
Funding Agency and Grant Number
Corresponding Author	Ignacio Garcia-Mansilla, MD, Division of Knee, Hospital Italiano de Buenos Aires, Juan Domingo Perón 4190, Buenos Aires 1109, Argentina. ignaciogmansilla@gmail.com
Key Words	Elderly dults; Knee osteoarthritis; Depression; Functional statu; Total knee arthroplasty
Core Tip	This study evaluates the relationship between depression and functional outcomes one year after total knee arthroplasty (TKA) in elderly patients. Results indicate that while depressive symptoms are common, they do not impact functional recovery as measured by the Knee Society Score. However, depression correlates with greater cognitive impairment, increased frailty, and higher risk of confusional syndrome. These findings suggest that depression should not be a barrier to TKA, though preoperative identification and management of depressive symptoms may improve postoperative quality of life and reduce complications.
Citation	Nicolino TI, Smietniansky M, Boietti B, Garcia-Mansilla I, Carbo L, Martinez CB. Impact of depression on functional status in elderly patients undergoing total knee arthroplasty. World J Methodol 2025; In press

Received	2024-10-28 02:41
Peer-Review Started	2024-11-20 01:41
To Make the First Decision
Return for Revision	2025-02-12 03:27
Revised	2025-02-26 15:11
Second Decision	2025-03-17 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-17 08:59
Articles in Press	2025-03-17 08:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-10 03:14

ISSN	2222-0682 (online)
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