Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	103029
Country	Croatia

Category	Oncology
Manuscript Type	Prospective Study
Article Title	Phase angle as a prognostic biomarker in metastatic colorectal cancer: A prospective trial
Manuscript Source	Unsolicited Manuscript
All Author List	Domina Kekez, Juraj Prejac, Gordan Adžić, Nikša Librenjak, Irma Goršić, Danijela Jonjić, Željko Krznarić, Goran Augustin and Stjepko Pleština
Funding Agency and Grant Number
Corresponding Author	Juraj Prejac, MD, PhD, Department of Oncology, University Hospital Centre Zagreb, Kišpatićeva 12, Zagreb 10000, Grad Zagreb, Croatia. jprejac@kbc-zagreb.hr
Key Words	Phase angle; Bioimpedance scale; Metastatic colorectal cancer; Treatment outcomes; First-line chemotherapy
Core Tip	Most patients with metastatic colorectal cancer (mCRC) experience malnutrition during their illness, resulting from both the disease and the treatment. Assessing the nutritional status of these patients is crucial due to its negative impact on treatment outcomes. Our objective was to establish the phase angle (PA) as a prognostic indicator for survival in mCRC patients. Our findings indicate that patients with a high PA (≥ 4.60°) have a considerably longer median progression-free survival during first-line treatment. PA, assessed using a bioelectrical impedance analysis scale, is a non-invasive and easily obtainable measure that can serve as an independent prognostic factor for survival in managing mCRC.
Citation	<p>Kekez D, Prejac J, Adžić G, Librenjak N, Goršić I, Jonjić D, Krznarić Ž, Augustin G, Pleština S. Phase angle as a prognostic biomarker in metastatic colorectal cancer: A prospective trial. <i>World J Gastrointest Oncol</i> 2025; 17(4): 103029</p>

Received	2024-11-06 12:55
Peer-Review Started	2024-11-06 12:56
To Make the First Decision
Return for Revision	2024-12-17 10:28
Revised	2024-12-29 12:45
Second Decision	2025-01-20 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-20 08:58
Articles in Press	2025-01-20 08:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-01-25 23:45
Typeset the Manuscript	2025-02-12 02:21

ISSN	1948-5204 (online)
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