| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Bin Wang, Bing Zhu, Ming-Ming Meng, Yi-Fan Wu, Yu Zhang, Dong-Ze Li, Hua Tian, Fu-Chuan Wang, Yi-Fan Lv, Qiu-Xia Ye and Fu-Quan Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| "14th Five-Year" Talent Training Program of Beijing Shijitan Hospital, Capital Medical University |
2023LJRCLFQ |
|
| Corresponding Author |
Fu-Quan Liu, MD, Professor, Center for Minimally Invasive Treatment of Liver Diseases, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian, Haidian district, Beijing 100080, China. lfuquan@aliyun.com |
| Key Words |
Liver cirrhosis; Portal hypertension; Transjugular intrahepatic portosystemic shunt; Hepatic encephalopathy; Liver failure; Carcinoma; Hepatocellular |
| Core Tip |
This study evaluates the impact of portal pressure gradient (PPG) reduction following transjugular intrahepatic portosystemic shunt (TIPS) on clinical outcomes in portal hypertension patients. Findings reveal that a significant PPG reduction (> 50%) post-TIPS is linked to decreased risks of rebleeding, shunt dysfunction, hepatocellular carcinoma, and mortality. However, it also raises the risk of hepatic encephalopathy and liver failure. Additionally, portal vein diameter influences the degree of PPG reduction. These insights highlight the need for personalized management strategies to optimize TIPS outcomes, balancing benefits and potential risks for improved patient prognosis. |
| Citation |
<p>Wang ZB, Zhu B, Meng MM, Wu YF, Zhang Y, Li DZ, Tian H, Wang FC, Lv YF, Ye QX, Liu FQ. Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients. <i>World J Hepatol</i> 2025; 17(3): 103261</p> |
| ISSN |
1948-5182 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
