Publication Name	World Journal of Virology
Manuscript ID	103347
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Chronic hepatitis B: Is it time for expanded antiviral treatment?
Manuscript Source	Invited Manuscript
All Author List	Manish Manrai, Atul A Jha, Aditya V Pachisia and Saurabh Dawra
Funding Agency and Grant Number
Corresponding Author	Manish Manrai, Professor, Department of Gastroenterology, Command Hospital, Lucknow-226002, Lucknow 226002, Uttar Pradesh, India. manishmanrai75@gmail.com
Key Words	Chronic hepatitis B; Hepatocellular carcinoma; Hepatitis B treatment guidelines; Occult B infection; Immune tolerant phase; Expanded treatment for hepatitis B
Core Tip	An estimated 254 million people, almost 3.3% of the world's population, are estimated to be living with chronic hepatitis B (CHB) infection. Without therapy, they are at risk of developing cirrhosis and might develop hepatocellular cancer (HCC). The prevention of HCC is a major challenge. We review the various clinical practice guidelines and consider emerging evidence that will foster research to consider the expansion of treatment indications of CHB.
Citation	Manrai M, Jha AA, Pachisia AV, Dawra S. Chronic hepatitis B: Is it time for expanded antiviral treatment? World J Virol 2025; In press

Received	2024-11-18 13:28
Peer-Review Started	2024-11-18 13:28
To Make the First Decision
Return for Revision	2025-03-21 06:28
Revised	2025-05-01 17:14
Second Decision	2025-07-11 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-11 05:53
Articles in Press	2025-07-11 05:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3249 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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