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Publication Name World Journal of Clinical Cases
Manuscript ID 103841
Country China
Category Pathology
Manuscript Type Retrospective Study
Article Title CXCR4 expression and clinicopathological features of endometrial endometrioid carcinoma with the microcystic, elongated, and fragmented pattern
Manuscript Source Unsolicited Manuscript
All Author List Ji-Xian Wang, Dan-Hua Shen and Xiao-Bo Zhang
Funding Agency and Grant Number
Corresponding Author Xiao-Bo Zhang, Department of Pathology, PeKing University People’s Hospital, No. 11 Xizhimen South Street, Beijing 100044, China. zhangxiaobo0326@163.com
Key Words Endometrioid endometrial carcinoma; Microcystic, elongated, and fragmented invasion; CXCR4; Clinicopathological features; Prognosis
Core Tip Endometrioid endometrial carcinoma (EEC) with the microcystic, elongated, and fragmented (MELF) invasion is a special invasive pattern, and its risk of lymphovascular space invasion and lymph node metastasis is significantly higher than that of the non-MELF group. The presence of MELF infiltration in EEC is associated with a higher expression of CXC chemokine receptor 4, which may play a role in the progression of the disease.
Citation <p>Wang JX, Shen DH, Zhang XB. CXCR4 expression and clinicopathological features of endometrial endometrioid carcinoma with the microcystic, elongated, and fragmented pattern. <i>World J Clin Cases</i> 2025; 13(21): 103841</p>
Received
2024-12-13 08:40
Peer-Review Started
2024-12-13 08:40
To Make the First Decision
Return for Revision
2025-03-04 01:34
Revised
2025-03-19 09:58
Second Decision
2025-04-07 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-07 09:14
Articles in Press
2025-04-07 09:14
Publication Fee Transferred
2025-03-24 12:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-16 10:27
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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