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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 103873
Country Kazakhstan
Category Pediatrics
Manuscript Type Retrospective Cohort Study
Article Title Comparative analysis on the efficacy of antenatal corticosteroids in preterm newborns in a Kazakhstani Tertiary Care Hospital setting
Manuscript Source Unsolicited Manuscript
All Author List Saltanat Sairankyzy, Ingkar Kinayatova, Diana Amangeldi, Ainura Zhumatova, Nishankul Bozhbanbayeva, Ainash Ismailova, Nazgul Akhtayeva and Olga An
Funding Agency and Grant Number
Corresponding Author Saltanat Sairankyzy, Associate Professor, PhD, Department of Neonatology, Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Tole bi str. 94, Almaty 050012, Kazakhstan. salta3105@mail.ru
Key Words Antenatal corticosteroids; Respiratory distress syndrome; Preterm newborns; Dexamethasone; Mechanical ventilation; Surfactant therapy
Core Tip This retrospective cohort study was aimed to evaluate the effect of antenatal steroid prophylaxis (ASP) on the general condition of preterm newborns. It demonstrates collected clinical data from January 2022 to February 2024 in Kazakhstan, Almaty region. 152 premature newborns with gestational ages between 24 and 34 weeks were analyzed depending on the completeness of ASP among them. Results show effect of ASP in prevention of respiratory distress syndrome and incidences of comorbidities related to respiratory, cardiovascular and digestive systems. In conclusion, findings suggest that ASP significantly improves neonatal outcomes, particularly in reducing birth asphyxia, primary resuscitation measures, need for lung ventilation including mechanical ventilation and nasal continuous positive airway pressure, and re-intubation cases.
Citation Sairankyzy S, Kinayatova I, Amangeldi D, Zhumatova A, Bozhbanbayeva N, Ismailova A, Akhtayeva N, An O. Comparative analysis on the efficacy of antenatal corticosteroids in preterm newborns in a Kazakhstani Tertiary Care Hospital setting. World J Clin Pediatr 2025; In press
Received
2024-12-11 08:20
Peer-Review Started
2024-12-11 08:23
To Make the First Decision
Return for Revision
2025-03-10 01:14
Revised
2025-03-22 20:48
Second Decision
2025-04-21 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-21 08:09
Articles in Press
2025-04-21 08:09
Publication Fee Transferred
2025-04-04 13:20
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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