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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 104568
Country China
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Clinical observation of combined transarterial chemoembolization and targeted therapy in postoperative recurrent colorectal cancer with liver metastasis
Manuscript Source Unsolicited Manuscript
All Author List Jian-Yu Liu, Zhi-Hui Liang, Jing-Lei Liu, Liang Li, Bao Cui and Tie-Gang Li
Funding Agency and Grant Number
Funding Agency Grant Number
2023 Hebei Provincial Medical Scientific Research Project Plan 20231304
Corresponding Author Jian-Yu Liu, Associate Chief Physician, MD, Department of Interventional Treatment, Bethune International Peace Hospital of PLA, No. 398 Zhongshan West Road, Qiaoxi District, Shijiazhuang 050082, Hebei Province, China. ljiany109527@163.com
Key Words Colorectal cancer; Liver metastasis; Transarterial chemoembolization; Targeted therapy; Bevacizumab; Treatment outcomes
Core Tip This study investigates the combination of transarterial chemoembolization and targeted therapies (bevacizumab, cetuximab, and panitumumab) for the treatment of postoperative recurrent colorectal cancer with liver metastasis. The results indicate that this multimodal approach improved overall survival (28 months) and progression-free survival (12 months), with bevacizumab showing superior outcomes. The treatment is well tolerated, with manageable adverse events, and significantly enhances the patients’ quality of life. This combination therapy has the potential to be an effective and safe strategy for this challenging clinical scenario.
Citation Liu JY, Liang ZH, Liu JL, Li L, Cui B, Li TG. Clinical observation of combined transarterial chemoembolization and targeted therapy in postoperative recurrent colorectal cancer with liver metastasis. World J Gastrointest Surg 2025; In press
Received
2025-03-26 09:29
Peer-Review Started
2025-03-26 09:29
To Make the First Decision
Return for Revision
2025-04-11 09:36
Revised
2025-04-21 16:18
Second Decision
2025-06-30 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-30 08:15
Articles in Press
2025-06-30 08:15
Publication Fee Transferred
2025-04-23 08:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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