Publication Name	World Journal of Clinical Cases
Manuscript ID	104742
Country	India

Category	Medicine, General & Internal
Manuscript Type	Case Report
Article Title	Tramadol overdose in total knee arthroplasty: A case report
Manuscript Source	Invited Manuscript
All Author List	Bushu Harna and Shivali Arya
Funding Agency and Grant Number
Corresponding Author	Bushu Harna, MD, Department of Orthopaedics, Indus International Hospital, No. 22 Ambala Road, Dera Bassi, Mohali 160507, Punjab, India. bushu.edu@gmail.com
Key Words	Overdose; Tramadol; Buprenorphine patch; Central nervous system depression; Respiratory depression; Case report
Core Tip	Clinicians should be aware of opioid toxicity in total knee arthroplasty patients. Cautions should be taken in the presence of kidney disorders. Tramadol and buprenorphine patches were commonly utilized in postoperative analgesia of knee arthroplasty. The combination of these drugs was not recommended and should be monitored for any adverse effects. It is better to use pre-emptive analgesia with minimum use of opioids.
Citation	Harna B, Arya S. Tramadol overdose in total knee arthroplasty: A case report. World J Clin Cases 2025; In press

Received	2024-12-31 10:35
Peer-Review Started	2024-12-31 10:35
To Make the First Decision
Return for Revision	2025-03-21 08:00
Revised	2025-04-27 11:50
Second Decision	2025-05-21 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-21 12:42
Articles in Press	2025-05-21 12:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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