Publication Name	World Journal of Hepatology
Manuscript ID	104761
Country	Canada

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Advances in the diagnosis and management of clinically significant portal hypertension in cirrhosis: A narrative review
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Yu Xie and Amine Benmassaoud
Funding Agency and Grant Number	Funding Agency Grant Number Quebec Health Research Fund Clinician Research Scholars Junior 1 No. 350546
Corresponding Author	Amine Benmassaoud, Assistant Professor, MD, Department of Gastroenterology and Hepatology, McGill University Health Centre, 1001 Decarie Blvd, Montreal H4A3J1, Quebec, Canada. amine.benmassaoud@mcgill.ca
Key Words	Decompensation; Hepatic venous pressure gradient; Portal pressure gradient; Endoscopic ultrasound; Liver stiffness; Spleen stiffness; Elastography; Cirrhosis; Portal hypertension
Core Tip	Portal hypertension (PH) is the main driver of morbidity and mortality in patients with cirrhosis. Over the last decade, there have been many critical developments in the diagnosis and management of this condition. The following review will provide the reader with a state-of-the-art appreciation of the most recent updates in the non-invasive and invasive diagnostic approaches, including the use of liver stiffness, spleen stiffness, and endoscopic ultrasound. A diagnostic algorithm is proposed to guide clinicians. We also discuss the role of pharmacological, endoscopic, and interventional therapeutic options to prevent and manage manifestations of PH.
Citation	<p>Xie XY, Benmassaoud A. Advances in the diagnosis and management of clinically significant portal hypertension in cirrhosis: A narrative review. <i>World J Hepatol</i> 2025; 17(6): 104761</p>

Received	2025-01-09 08:33
Peer-Review Started	2025-01-15 00:41
To Make the First Decision
Return for Revision	2025-03-27 10:27
Revised	2025-04-09 07:58
Second Decision	2025-05-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-18 12:23
Articles in Press	2025-05-18 12:23
Publication Fee Transferred	2025-04-18 19:39
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-16 07:25

ISSN	1948-5182 (online)
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