Publication Name	World Journal of Gastroenterology
Manuscript ID	104952
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Perirenal fat area is a preoperative predictor of hypertension resolution after laparoscopic sleeve gastrectomy: Generalized additive models
Manuscript Source	Unsolicited Manuscript
All Author List	Yue Li, Kai-Yuan Zheng, Zeng-Lin Liu, Tian-Ming Yu, Wen-Jie Zhang, Ming-Wei Zhong and San-Yuan Hu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82270914, 82401043
Corresponding Author	San-Yuan Hu, Chief Physician, MD, Professor, Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, No. 107 West Wenhua Road, Jinan 250012, Shandong Province, China. husanyuan1962@hotmail.com
Key Words	Laparoscopic sleeve gastrectomy; Obesity; Hypertension resolution; Perirenal adipose tissue; Perirenal fat area
Core Tip	In this retrospective single-center study, we found that the preoperative perirenal fat area (PrFA), an important factor linking obesity and hypertension, is an independent predictor of hypertension resolution after laparoscopic sleeve gastrectomy. Particularly, PrFA could achieve an accuracy of approximately 85% in predicting resolution using the generalized additive model. Based on the curvilinear correlation between PrFA and resolution rate, we set 18 cm2 as the cutoff value for PrFA and found that patients with PrFA < 18 cm2 had a higher hypertension resolution rate than those with PrFA ≥ 18 cm2 [87% vs 68.1%; odds ratio (95% confidence interval) = 3.513 (1.367-9.902), P = 0.012].
Citation	<p>Li Y, Zheng KY, Liu ZL, Yu TM, Zhang WJ, Zhong MW, Hu SY. Perirenal fat area is a preoperative predictor of hypertension resolution after laparoscopic sleeve gastrectomy: Generalized additive models. <i>World J Gastroenterol</i> 2025; 31(12): 104952</p>

Received	2025-01-10 08:39
Peer-Review Started	2025-01-10 08:39
To Make the First Decision
Return for Revision	2025-02-12 10:35
Revised	2025-02-16 04:11
Second Decision	2025-02-28 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-28 06:10
Articles in Press	2025-02-28 06:10
Publication Fee Transferred	2025-02-18 03:12
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-13 08:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com