Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	104954
Country	China

Category	Pathology
Manuscript Type	Minireviews
Article Title	Clinicopathologic features of allied disorders of Hirschsprung disease and status update
Manuscript Source	Unsolicited Manuscript
All Author List	Miao Lu
Funding Agency and Grant Number
Corresponding Author	Miao Lu, Professor, Department of Pathology, Pingshan District Central Hospital of Shenzhen, No. 51 Julongshan Road, Kengzi Subdistric, Shenzhen 518100, Guangdong Province, China. lumiaolm0725@163.com
Key Words	Congenital megacolon; Homologous disease; Enteric ganglion; Abnormal development; Allied disorders of Hirschsprung disease
Core Tip	While allied disorders of Hirschsprung disease share clinical similarities with Hirschsprung’s disease (Q43.1), the pathologic manifestation and therapeutic approach differ from Hirschsprung’s disease. To address the challenges in pathologic diagnosis, it is still necessary to develop a consensus on a reliable classification method at the international level. First, the global standard diagnostic criteria should be established and artificial intelligence technology can be used to do deep learning on the global data. These advances will help overcome diagnostic obstacles and enhance the accuracy of pathologic diagnosis. To produce clinical guidelines, additional data collecting, follow-up, and data analysis are necessary to acquire improved treatment methods, prognosis, etiology, and genetic investigations.
Citation	Lu M. Clinicopathologic features of allied disorders of Hirschsprung disease and status update. World J Gastrointest Surg 2025; In press

Received	2025-01-08 09:16
Peer-Review Started	2025-01-08 09:16
To Make the First Decision
Return for Revision	2025-03-19 02:47
Revised	2025-04-29 07:13
Second Decision	2025-06-10 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-10 06:22
Articles in Press	2025-06-10 06:22
Publication Fee Transferred	2025-05-09 08:14
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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