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Publication Name World Journal of Clinical Oncology
Manuscript ID 105322
Country China
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Helicobacter pylori infection promotes the progression of gastric cancer by regulating the expression of DMBT1
Manuscript Source Unsolicited Manuscript
All Author List Xiu Zhou, Lin-Qing Wang, Shuai Song, Mei Xu and Chang-Ping Li
Funding Agency and Grant Number
Corresponding Author Chang-Ping Li, MD, Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Luzhou 646000, Sichuan Province, China. 506854209@qq.com
Key Words Helicobacter pylori; Gastric cancer; Deleted in malignant brain tumors 1; Proliferation; Metastasis
Core Tip The main reason for gastric cancer (GC) is Helicobacter pylori (H. pylori). The annual global burden of GC continues to increase. Our study investigated the influence of deleted in malignant brain tumors 1 induced by H. pylori on the proliferation and metastasis of GC. Using human GC cells, we concluded that H. pylori promote GC cell proliferation, metastasis, and invasion through down-regulation of deleted in malignant brain tumors 1 and facilitates GC development through cell function experiments and gene expression experiments.
Citation <p>Zhou X, Wang LQ, Song S, Xu M, Li CP. Helicobacter pylori infection promotes the progression of gastric cancer by regulating the expression of DMBT1. <i>World J Clin Oncol</i> 2025; 16(5): 105322</p>
Received
2025-01-18 08:06
Peer-Review Started
2025-01-18 08:07
To Make the First Decision
Return for Revision
2025-02-19 09:46
Revised
2025-03-04 18:32
Second Decision
2025-03-26 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-26 09:06
Articles in Press
2025-03-26 09:06
Publication Fee Transferred
2025-03-07 05:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-08 01:01
ISSN 2218-4333 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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