| Category |
Integrative & Complementary Medicine |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Effect of electroacupuncture combined with Tuina therapy on gut microbiota in patients with knee osteoarthritis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao Guo, Liang Guo, Qing-Ze Lu, Hui Xie, Juan Chen, Wen-Li Su, Yuan Tian, Xiao-Hua Li, Hong-Lei Miao, Yi Zhang, Yan Yang, Cai Liao, Jun-Yuan Deng, Yun-Hao Yang, Cheng-Lin Tang and He-Jing Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chongqing Municipal Health and Family Planning Commission and Chongqing Municipal Science and Technology Commission Jointly Funded Key Research Projects in Traditional Chinese Medicine |
ZY201801007 |
|
| Corresponding Author |
Cheng-Lin Tang, Professor, College of Traditional Chinese Medicine, Chongqing Medical University, No. 1 Medical School Road, Yuzhong District, Chongqing 400016, China. tangchenglin@cqmu.edu.cn |
| Key Words |
Knee osteoarthritis; Tuina; Electroacupuncture; Gut microbiota; Randomized controlled trial |
| Core Tip |
This study introduces a novel therapeutic approach combining electroacupuncture and Tuina therapy to alleviate pain and enhance joint flexibility in knee osteoarthritis (KOA). It highlights the significant role of gut microbiota in this process, demonstrating how ET can reduce pathogenic bacteria and increase beneficial ones to mitigate inflammatory responses, indirectly suggesting a gut-joint axis influence on KOA. This innovative perspective opens new avenues for understanding and treating inflammatory joint diseases, offering fresh therapeutic targets and strategies. |
| Citation |
<p>Guo X, Guo L, Lu QZ, Xie H, Chen J, Su WL, Tian Y, Li XH, Miao HL, Zhang Y, Yang Y, Liao C, Deng JY, Yang YH, Tang CL, Liu HJ. Effect of electroacupuncture combined with Tuina therapy on gut microbiota in patients with knee osteoarthritis. <i>World J Gastroenterol</i> 2025; 31(18): 105495</p> |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
