Publication Name	World Journal of Diabetes
Manuscript ID	105496
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Study
Article Title	Does low physical activity cause cognitive decline in elderly type 2 diabetes patients: A propensity score matching analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Xin Ma, Jing Li, Si-Cong Si, Huan Zhao, Jia Liu, Long-Feng Lv, Kai Yang and Wei Yang
Funding Agency and Grant Number	Funding Agency Grant Number Capital Funds for Health Improvement and Research 2024-2-1033 Beijing Municipal Administration of Hospitals Incubating Program PX2022032 Post-subsidy Fund from the National Clinical Research Center, the Ministry of Science and Technology of China 303-01-001-0272-08 Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes JYY2023-13
Corresponding Author	Wei Yang, Associate Professor, MD, Department of Geriatrics, Xuanwu Hospital Capital Medical University, National Clinical Research Center for Geriatric Diseases, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. yangw_79@163.com
Key Words	Type 2 diabetes mellitus; Propensity score matching; Cognitive impairment; Low physical activity
Core Tip	The relationship between physical activity and cognitive impairment in elderly diabetes patients remains controversial. For this investigation of risk factors for cognitive impairment in these patients, we applied propensity score matching between groups with low and non-low levels of physical activity. After adjusting for confounders and balancing baseline differences, we surprisingly found no significant association between low physical activity and cognitive decline in this population, challenging prior research. These results emphasize the complexity of factors affecting cognitive decline in diabetes. Potential contributors include social environment, sarcopenia, frailty, and multifactorial elements, offering new perspectives on managing cognitive health in diabetic populations.
Citation	Ma YX, Li J, Si SC, Zhao H, Liu J, Lv LF, Yang K, Yang W. Does low physical activity cause cognitive decline in elderly type 2 diabetes patients: A propensity score matching analysis. World J Diabetes 2025; In press

Received	2025-01-24 07:06
Peer-Review Started	2025-01-24 07:07
To Make the First Decision
Return for Revision	2025-03-19 08:47
Revised	2025-04-07 10:22
Second Decision	2025-05-09 09:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-20 07:23
Articles in Press	2025-05-20 07:23
Publication Fee Transferred	2025-04-10 02:27
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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