| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in cirrhosis patients: Prospective comparative study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Peng Wu, Ying-Fei Wang, Feng-Wei Shi, Wen-Hui Cao, Jie Sun, Liu Yang, Fang-Ping Ding, Cai-Xia Hu, Wei-Wei Kang, Jing Han, Rong-Hui Yang, Qing-Kun Song, Jia-Wei Jin, Hong-Bo Shi and Ying-Min Ma |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
No. 2022YFC2305002 |
| Beijing Natural Science Foundation |
No. 7232079 |
| Middle-aged and Young Talent Incubation Programs (Clinical Research) of Beijing Youan Hospital |
No. BJYAYY-YN2022-12 |
| Middle-aged and Young Talent Incubation Programs (Clinical Research) of Beijing Youan Hospital |
No. BJYAYY-YN2022-13 |
| Middle-aged and Young Talent Incubation Programs (Clinical Research) of Beijing Youan Hospital |
No. BJYAYY-YN2022-01 |
| China Postdoctoral Science Foundation |
No. 2023M732410 |
| China Postdoctoral Science Foundation |
No. 2024T170595 |
|
| Corresponding Author |
Ying-Min Ma, Chief Physician, Full Professor, Beijing Institute of Hepatology, Department of Respiratory and Critical Care Medicine, Beijing Youan Hospital, Capital Medical University, No. 8 Xi Tou Tiao, Youanmenwai Street, Fengtai District, Beijing 100069, China. ma.yingmin@163.com |
| Key Words |
Liver cirrhosis; Hepatopulmonary syndrome; Prediction model; Clinical parameters; Biomarkers |
| Core Tip |
This study involved 320 patients with liver cirrhosis, among whom 101 were diagnosed with intrapulmonary vascular dilatation (IPVD), and of these, 54 were diagnosed with hepatopulmonary syndrome (HPS). Nine potential biomarkers possibly related to HPS were tested, and the clinical parameters and biomarker levels of three patient groups were compared. Predictive models for IPVD and HPS were built respectively based on patients’ clinical information and three biomarkers: Sphingosine 1 phosphate, angiopoietin-2, and platelet-derived growth factor BB. |
| Citation |
<p>Wu ZP, Wang YF, Shi FW, Cao WH, Sun J, Yang L, Ding FP, Hu CX, Kang WW, Han J, Yang RH, Song QK, Jin JW, Shi HB, Ma YM. Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in cirrhosis patients: Prospective comparative study. <i>World J Gastroenterol</i> 2025; 31(15): 105720</p> |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
