Publication Name	World Journal of Clinical Cases
Manuscript ID	105911
Country	Spain

Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Observational Study
Article Title	Low salivary uric acid levels are independently associated with periodontitis
Manuscript Source	Invited Manuscript
All Author List	Leonardo Lorente, Esther Hernández Marrero, Pedro Abreu-Gonzalez, Angel Daniel Lorente Martín, Agustín F González-Rivero, María José Marrero González, Carmen Hernández Marrero, Olga Hernández Marrero, Alejandro Jiménez and Cándido Manuel Hernández Padilla
Funding Agency and Grant Number
Corresponding Author	Leonardo Lorente, MD, PhD, Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna 38320, Spain. lorentemartin@msn.com
Key Words	Oxidation; Salivary; Uric acid; Periodontitis; Gingivitis
Core Tip	Lower salivary uric acid concentrations, the most abundant antioxidant agent in saliva, have been observed in patients with periodontitis compared to individuals with periodontal health. The two novel findings of our research were, first, that low salivary uric acid concentrations are independently associated with periodontitis, even after accounting for established risk factors. Second, salivary uric acid levels show a negative correlation with periodontitis severity.
Citation	<p>Lorente L, Hernández Marrero E, Abreu-Gonzalez P, Lorente Martín AD, González-Rivero AF, Marrero González MJ, Hernández Marrero C, Hernández Marrero O, Jiménez A, Hernández Padilla CM. Low salivary uric acid levels are independently associated with periodontitis. <i>World J Clin Cases</i> 2025; 13(21): 105911</p>

Received	2025-02-10 04:47
Peer-Review Started	2025-02-10 04:49
To Make the First Decision
Return for Revision	2025-03-12 06:53
Revised	2025-03-13 16:29
Second Decision	2025-03-20 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-21 02:20
Articles in Press	2025-03-21 02:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-16 03:05

ISSN	2307-8960 (online)
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