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5/21/2025 9:02:57 AM | Browse: 9 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 105981
Country China
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Pan-cancer analysis of UDP-glucose 6-dehydrogenase in human tumors and exploring UDP-glucose 6-dehydrogenase’s function in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Xu Cao, Shi-Hao Zheng, Jiu-Mei Shen, Si-Ze Li, Li Hou, Jia-Xin Zhang, Xiao-Ke Li, Hong-Bo Du, Li-Ping Zhang, Yong-An Ye and Xiao-Bin Zao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No.82405314
Horizontal Project of Dongzhimen Hospital No: HX-DZM-202405
Traditional Chinese Medicine Foundation of Xiamen XWZY-2023-0616
Project of Beijing University of Chinese Medicine No. DZMG-QNZX-24015
Corresponding Author Xiao-Bin Zao, Assistant Professor, PhD, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 116 Cuiping West Road, Tongzhou District, Beijing 100700, China. a3417@bucm.edu.cn
Key Words UDP-glucose 6-dehydrogenase; Hepatocellular carcinoma; Bioinformatics; Pancancer; Pentose and glucuronate interconversion
Core Tip Our study elucidates that UDP-glucose 6-dehydrogenase (UGDH) could be useful as a valuable prognostic biomarker and potential therapeutic target in many cancers, especially liver and lung cancer. UGDH could promote the proliferation of hepatocellular carcinoma cells, possibly by modulating the pentose and glucuronate interconversion pathway.
Citation Cao X, Zheng SH, Shen JM, Li SZ, Hou L, Zhang JX, Li XK, Du HB, Zhang LP, Ye YA, Zao XB. Pan-cancer analysis of UDP-glucose 6-dehydrogenase in human tumors and exploring UDP-glucose 6-dehydrogenase’s function in hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press
Received
2025-02-14 08:47
Peer-Review Started
2025-02-14 08:48
To Make the First Decision
Return for Revision
2025-03-04 07:34
Revised
2025-03-26 14:31
Second Decision
2025-05-21 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-21 09:02
Articles in Press
2025-05-21 09:02
Publication Fee Transferred
2025-03-31 09:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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