Publication Name	World Journal of Methodology
Manuscript ID	106148
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Uncovering the role of microbiota and fecal microbiota transplantation in Crohn’s disease: Current advances and future hurdles
Manuscript Source	Invited Manuscript
All Author List	Jai P Singh, Maryam Aleissa, Gautham Chitragari, Ernesto Raul Drelichman, Vijay K Mittal and Jasneet Singh Bhullar
Funding Agency and Grant Number
Corresponding Author	Jai P Singh, Department of Surgery, Henry Ford Providence Hospital, Michigan State University College of Human Medicine, *Jai P. Singh: <email>drjp04@gmail.com</email>, Southfield, MI 48075, United States. drjp04@gmail.com
Key Words	Microbiota; Microbiome; Dysbiosis; Fecal microbiota transplantation; Crohn's disease
Core Tip	This article reviews the role of microbiota in Crohn’s disease (CD) and the effects of fecal microbiota transplantation. CD is a chronic, relapsing condition with a complex pathogenesis involving genetic and environmental factors. The gut microbiota, crucial for various bodily functions, shows dysbiosis in CD, with a reduction in beneficial microbes. This review highlights recent developments in understanding microbiota’s role in CD and its potential in treatment strategies.
Citation	Singh JP, Aleissa M, Chitragari G, Drelichman ER, Mittal VK, Bhullar JS. Uncovering the role of microbiota and fecal microbiota transplantation in Crohn’s disease: Current advances and future hurdles. World J Methodol 2025; In press

Received	2025-02-18 04:08
Peer-Review Started	2025-02-19 05:41
To Make the First Decision
Return for Revision	2025-03-14 11:17
Revised	2025-03-26 23:42
Second Decision	2025-04-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-17 09:05
Articles in Press	2025-04-17 09:05
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Typeset the Manuscript

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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