Publication Name	World Journal of Orthopedics
Manuscript ID	106181
Country	Brazil

Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Systematic Reviews
Article Title	Update on synthetic biomaterials combined with fibrin derivatives for regenerative medicine: Applications in bone defect treatment: Systematic review
Manuscript Source	Invited Manuscript
All Author List	Bruna Trazzi Pagani, Marcelie Priscila de Oliveira Rosso, Matheus Bento Medeiros Moscatel, Beatriz Flavia de Moraes Trazzi, Marcelo Rodrigues da Cunha, João Paulo Mardegan Issa, Daniela Vieira Buchaim and Rogério Leone Buchaim
Funding Agency and Grant Number
Corresponding Author	Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla 9-75, Bauru 17012-901, Brazil. rogerio@fob.usp.br
Key Words	Biomaterials; Bone regeneration; Fibrin sealant; Hydroxyapatite; Orthopedics; Dentistry; Regenerative medicine
Core Tip	The integration of synthetic biomaterials and fibrin composites is a promising strategy in regenerative medicine, demonstrating high biocompatibility and effectiveness in bone formation. It also represents progress in the pursuit of more accessible and clinically applicable solutions for bone reconstruction.
Citation	<p>Pagani BT, Rosso MPO, Moscatel MBM, Trazzi BFM, da Cunha MR, Issa JPM, Buchaim DV, Buchaim RL. Update on synthetic biomaterials combined with fibrin derivatives for regenerative medicine: Applications in bone defect treatment: Systematic review. <i>World J Orthop</i> 2025; 16(5): 106181</p>

Received	2025-02-18 03:05
Peer-Review Started	2025-02-18 03:06
To Make the First Decision
Return for Revision	2025-03-19 06:14
Revised	2025-04-01 01:17
Second Decision	2025-04-21 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-21 08:32
Articles in Press	2025-04-21 08:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-05-05 10:12

ISSN	2218-5836 (online)
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