Publication Name	World Journal of Methodology
Manuscript ID	106216
Country	Greece

Category	Orthopedics
Manuscript Type	Basic Study
Article Title	Effect of alpha-tocopherol and OTR-4131 on muscle degeneration after rotator cuff tear in rats: An experimental protocol
Manuscript Source	Invited Manuscript
All Author List	Stavros Stamiris, Angeliki Cheva, Michael Potoupnis, Elissavet Anestiadou, Dimitrios Stamiris, Chryssa Bekiari, Antonia Loukousia, Papavasiliou Kyriakos, Eleftherios Tsiridis and Ioannis Sarris
Funding Agency and Grant Number
Corresponding Author	Elissavet Anestiadou, MD, Fourth Academic Department of Surgery, School of Medical, Aristotle University of Thessaloniki, Leoforos Papanikolaou, Thessaloniki 54124, Greece. elissavetxatz@gmail.com
Key Words	Alpha-tocopherol; OTR-4131; Rotator cuff tears; Experimental protocol; Muscle atrophy; Fatty infiltration
Core Tip	This experimental protocol outlines a novel approach to investigating the use of therapeutic agents, following massive rotator cuff tears in a rat model. By systematically assessing muscle atrophy, fatty infiltration, and fibrosis, this study aims to establish a standardized methodology for evaluating potential therapeutic agents. The findings from this protocol could provide critical insights into muscle preservation strategies, potentially informing future preclinical and clinical interventions for rotator cuff repair.
Citation	Stamiris S, Cheva A, Potoupnis M, Anestiadou E, Stamiris D, Bekiari C, Loukousia A, Kyriakos P, Tsiridis E, Sarris I. Effect of alpha-tocopherol and OTR-4131 on muscle degeneration after rotator cuff tear in rats: An experimental protocol. World J Methodol 2025; In press

Received	2025-02-21 07:01
Peer-Review Started	2025-02-26 05:37
To Make the First Decision
Return for Revision	2025-04-18 01:12
Revised	2025-04-27 13:21
Second Decision	2025-06-27 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-27 03:47
Articles in Press	2025-06-27 03:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
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