Publication Name	World Journal of Clinical Oncology
Manuscript ID	106228
Country	China

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Swollen lymph node metastasis and survival in gastric cancer: Multi-institutional post-resection analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Jing-Li Cui, Kai Zhao, Xiang-Li Li, Fei Wang, Yong-Sheng Yang and Xiao Zheng
Funding Agency and Grant Number	Funding Agency Grant Number The Shandong Provincial Medical and Health Science and Technology Youth Project, China No. 202304081355 The Weifang Youth Medical Talent Lift Project, China The Science and Technology Development Project of Affiliated Hospital of Shandong Second Medical University, China No. 2023FYQ004
Corresponding Author	Xiao Zheng, MD, PhD, Professor, Department of Gastrointestinal Surgery, The Affiliated Taian City Central Hospital of Qingdao University, No. 29 Longtan Road, Tai’an 271000, Shandong Province, China. zhengxiao@qdu.edu.cn
Key Words	Gastric cancer; Swollen lymph node metastasis; Neoadjuvant chemotherapy; Prognosis; Survival
Core Tip	This multi-center retrospective study of 1532 gastric cancer patients demonstrates that swollen lymph node (LN) metastasis (SLNM) is an independent prognostic factor, particularly in N0-1 stage patients. Using propensity score matching and Cox regression, SLNM was associated with a 48% increased mortality risk (hazard ratio = 1.48). Findings suggest integrating SLNM into tumor–node–metastasis staging could refine prognosis prediction and guide adjuvant therapy decisions, emphasizing the clinical value of meticulous LN dissection and pathological evaluation.
Citation	Cui JL, Zhao K, Li XL, Wang F, Yang YS, Zheng X. Swollen lymph node metastasis and survival in gastric cancer: Multi-institutional post-resection analysis. World J Clin Oncol 2025; In press

Received	2025-02-27 05:53
Peer-Review Started	2025-02-27 05:53
To Make the First Decision
Return for Revision	2025-03-27 14:41
Revised	2025-04-08 06:11
Second Decision	2025-04-27 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-27 08:54
Articles in Press	2025-04-27 08:54
Publication Fee Transferred	2025-04-10 12:20
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Typeset the Manuscript

ISSN	2218-4333 (online)
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