Publication Name	World Journal of Gastroenterology
Manuscript ID	106406
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Comparative study on the pathogenesis of Crohn’s disease and ulcerative colitis
Manuscript Source	Unsolicited Manuscript
All Author List	Qi-Hang Yang and Chuang-Nian Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Tianjin Municipal Science and Technology Commission Grant 24ZXRKSY00010 Program for Innovative Research Team in Peking Union Medical College, CAMS Initiative for Innovative Medicine 2023-I2M-2-008
Corresponding Author	Chuang-Nian Zhang, Senior Researcher, Chinese Academy of Medical Science & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Engineering Research Center of Pulmonary and Critical Care Medicine Technology and Device (Ministry of Education), Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Tianjin Institutes of Health Science, No. 236 Baidi Road, Nankai District, Tianjin 300192, China. cnzhang@mail.nankai.edu.cn
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Pathogenesis; Unique pathogenesis of Crohn’s disease; Unique pathogenesis of ulcerative colitis; Immune responses; Gene function; Microbes
Core Tip	Six common and fourteen unique aspects of the pathogenesis of inflammatory bowel disease, primarily Crohn’s disease and ulcerative colitis, illustrate the causes and beneficial factors of resistance to inflammatory bowel disease, providing critical insights for targeted treatment of Crohn’s disease and ulcerative colitis. Utilizing the main contents of this paper allows for the development of comprehensive interventions that reduce harmful influences, enhance protective factors and use an integrative approach to address the diseases for the benefit of the human being.
Citation	Yang QH, Zhang CN. Comparative study on the pathogenesis of Crohn’s disease and ulcerative colitis. World J Gastroenterol 2025; In press

Received	2025-02-26 06:05
Peer-Review Started	2025-02-26 06:05
To Make the First Decision
Return for Revision	2025-03-21 22:37
Revised	2025-03-25 07:41
Second Decision	2025-04-25 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-25 05:39
Articles in Press	2025-04-25 05:39
Publication Fee Transferred	2025-03-26 02:37
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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