Publication Name	World Journal of Radiology
Manuscript ID	106438
Country	United Kingdom

Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Factors affecting disease control after pituitary tumor resection in acromegaly: What is the current evidence?
Manuscript Source	Invited Manuscript
All Author List	Cornelius J Fernandez, Vijaya Lakshmi, Abul Bashar M Kamrul-Hasan and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author	Joseph M Pappachan, FRCP, MD, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, Oxford Road, Manchester M15 6BH, United Kingdom. drpappachan@yahoo.co.in
Key Words	Acromegaly; Pituitary neuroendocrine tumor; Somatostatin receptor; Somatostatin receptor ligands; Transsphenoidal surgery
Core Tip	Transsphenoidal surgery is the most effective treatment for acromegaly. Alone, it could achieve a remission rate of 73%. However, when followed by medical therapy, the remission rates could reach 87%. The biochemical remission rates following surgery and medical therapy are highly variable depending on various clinical, biochemical, radiological, histopathological and genetic parameters. Earlier studies have identified tumor size, tumor invasion, T2-weighted hyperintensity, granulation, and pretreatment growth hormone and/or insulin-like growth factor 1 levels as important prognostic markers. A study published by Alvarez et al noted that preoperative pituitary neuroendocrine tumor volume could predict postoperative remission.
Citation	Fernandez CJ, Lakshmi V, Kamrul-Hasan ABM, Pappachan JM. Factors affecting disease control after pituitary tumor resection in acromegaly: What is the current evidence? World J Radiol 2025; In press

Received	2025-02-26 09:44
Peer-Review Started	2025-02-26 09:45
To Make the First Decision
Return for Revision	2025-04-16 10:46
Revised	2025-04-18 09:22
Second Decision	2025-05-21 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-21 13:59
Articles in Press	2025-05-21 13:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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