Publication Name	World Journal of Clinical Oncology
Manuscript ID	106498
Country	Greece

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Endoscopic assessment of rectal cancer response after neoadjuvant chemoradiotherapy: A narrative literature review
Manuscript Source	Invited Manuscript
All Author List	Fotios Seretis, Antonia Panagaki, Paraskevas Gkolfakis, Georgios Tziatzios and Konstantina Paraskeva
Funding Agency and Grant Number
Corresponding Author	Georgios Tziatzios, MD, PhD, Department of Gastroenterology, General Hospital of Nea Ionia “Konstantopoulio-Patision”, Theodore Konstantopoulou 3-5, Nea Ionia, Athens 14233, Attiki, Greece. g_tziatzios@yahoo.gr
Key Words	Endoscopic assessment; Clinical response; Rectal cancer; Neoadjuvant; Total neoadjuvant; Predictors of response; Pathologic complete response
Core Tip	Endoscopic assessment of rectal cancer response in patients undergoing neoadjuvant treatment can predict pathologic complete response when specific criteria are applied. Endoscopic features such as absence of nodularity and ulceration and the presence of a flat, white scar with telangiectasia, if used in conjunction, have a diagnostic accuracy of more than 80% in predicting subsequent pathologic complete response in curative intent surgery. Therefore, it can be utilized for safe omission of surgery in organ-preservation strategies.
Citation	Seretis F, Panagaki A, Gkolfakis P, Tziatzios G, Paraskeva K. Endoscopic assessment of rectal cancer response after neoadjuvant chemoradiotherapy: A narrative literature review. World J Clin Oncol 2025; In press

Received	2025-02-28 13:11
Peer-Review Started	2025-02-28 13:11
To Make the First Decision
Return for Revision	2025-04-01 12:58
Revised	2025-06-17 08:18
Second Decision	2025-10-11 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-11 13:21
Articles in Press	2025-10-11 13:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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