Publication Name	World Journal of Clinical Oncology
Manuscript ID	106511
Country	Greece

Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Changing paradigms in evaluating adrenal incidentalomas: Bayesian evaluation of [18F]Fluorodeoxyglucose positron emission tomography use, honed on adrenocortical carcinoma
Manuscript Source	Invited Manuscript
All Author List	Ioannis Ilias and Georgios Meristoudis
Funding Agency and Grant Number
Corresponding Author	Ioannis Ilias, Director, MD, PhD, Department of Endocrinology, Hippocration General Hospital, 63, Evrou Street, Athens GR-11527, Greece. iiliasmd@yahoo.com
Key Words	Adrenal gland neoplasms; Diagnosis; Epidemiology; Positron emission tomography; Bayes theorem
Core Tip	[18F]Fluorodeoxyglucose positron emission tomography (FDG PET) diagnostic performance for adrenal incidentalomas (AdIn) was evaluated based on their size as measured on computed tomography (CT) and their unenhanced density in Hounsfield units (HU), using a 20 HU cutoff to assess adrenocortical carcinoma (ACC) risk. The likelihood ratios for positive/negative tests do not meet the usual thresholds, respectively, indicating strong but not definitive diagnostic accuracy. FDG PET should be combined with CT or magnetic resonance imaging for optimal assessment of AdIns.
Citation	Ilias I, Meristoudis G. Changing paradigms in evaluating adrenal incidentalomas: Bayesian evaluation of [18F]Fluorodeoxyglucose positron emission tomography use, honed on adrenocortical carcinoma. World J Clin Oncol 2025; In press

Received	2025-02-28 12:14
Peer-Review Started	2025-02-28 12:14
To Make the First Decision
Return for Revision	2025-03-18 09:18
Revised	2025-03-20 10:53
Second Decision	2025-04-25 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-25 06:51
Articles in Press	2025-04-25 06:51
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ISSN	2218-4333 (online)
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