Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	106672
Country	United States

Category	Pathology
Manuscript Type	Minireviews
Article Title	Acellular mucin in neoplastic and non-neoplastic conditions of the lower gastrointestinal tract
Manuscript Source	Invited Manuscript
All Author List	Noureldien Darwish, Lynn Guo, Eundong Park and Hwajeong Lee
Funding Agency and Grant Number
Corresponding Author	Hwajeong Lee, Professor, Department of Pathology and Laboratory Medicine, Albany Medical Center, 43 New Scotland Ave, Albany, NY 12208, United States. leeh5@amc.edu
Key Words	Acellular mucin; Mucinous adenocarcinoma; Pseudomyxoma peritonei; Low-grade appendiceal mucinous neoplasm; Interval appendectomy
Core Tip	Acellular mucin in both neoplastic and non-neoplastic lower gastrointestinal tract conditions may complicate diagnosis, prognostication and management. In colorectal and appendiceal mucinous neoplasms, it plays a role in tumor classification and staging. In non-neoplastic conditions, the presence of acellular mucin and related epithelial changes may mimic neoplasm and lead to additional work-up. This review highlights the diagnostic and prognostic implications of acellular mucin in neoplastic and non-neoplastic conditions, emphasizing the need for standardized approaches to improve pathological interpretation and management.
Citation	<p>Darwish N, Guo L, Park E, Lee H. Acellular mucin in neoplastic and non-neoplastic conditions of the lower gastrointestinal tract. <i>World J Gastrointest Surg</i> 2025; 17(7): 106672</p>

Received	2025-03-04 11:53
Peer-Review Started	2025-03-04 11:54
To Make the First Decision
Return for Revision	2025-03-26 11:23
Revised	2025-04-03 23:09
Second Decision	2025-05-22 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-22 07:25
Articles in Press	2025-05-22 07:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-30 14:13

ISSN	1948-9366 (online)
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