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Articles in Press
6/10/2025 4:08:16 AM | Browse: 7 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic value of immune-inflammation and nutritional indices in advanced hepatocellular carcinoma patients receiving immunotherapy with compound Kushen injection
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yong-Fu Zhu, Dong-Wei Zhang, Ming Zhang, Ming-Hui Yu, Shao-Hu Zhang and Yue-Yue Wu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| 2022 Anhui Provincial Health Commission Scientific Research Project |
No. AHWJ2022b05 |
| 2022 Scientific Research Project of Anhui University of Chinese Medicine |
No. 2022AH050415 |
| Horizontal Project |
No. 2022HZ009 |
| 2024 Open Project of the Key Laboratory of Xin’an Medicine, Ministry of Education |
No. 2024xayx02 |
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| Corresponding Author |
Yong-Fu Zhu, Department of The First Oncology, The First Affiliated Hospital of Anhui University of Chinese Medicine, No. 117 Meishan Road, Hefei 230031, Anhui Province, China. zyf240@ahtcm.edu.cn |
| Key Words |
Immunotherapy; Advanced hepatocellular carcinoma; Ascites; Systemic immune inflammation index; Prognostic nutritional index |
| Core Tip |
A scoring system combining the systemic immune-inflammation index and prognostic nutritional index has efficacy for evaluating treatment response and prognosis in patients with advanced hepatocellular carcinoma receiving immunotherapy and compound kushen injection. The systemic immune-inflammation index-prognostic nutritional index score identifies patients at high risk, predicts progression-free and overall survival, and supports personalized treatment planning. By improving the inflammatory and nutritional status, compound kushen injection enhances the therapeutic outcomes of immunotherapy, particularly in patients with ascites. This approach contributes to a more refined assessment of patient prognosis and a deeper understanding of the interplay among nutrition, immunity, and inflammation in hepatocellular carcinoma management. |
| Citation |
Zhu YF, Zhang DW, Zhang M, Yu MH, Zhang SH, Wu YY. Prognostic value of immune-inflammation and nutritional indices in advanced hepatocellular carcinoma patients receiving immunotherapy with compound Kushen injection. World J Gastrointest Oncol 2025; In press |
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Received |
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2025-03-28 09:00 |
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Peer-Review Started |
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2025-03-28 09:00 |
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To Make the First Decision |
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Return for Revision |
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2025-04-11 09:38 |
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Revised |
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2025-04-21 14:44 |
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Second Decision |
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2025-06-10 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-10 04:08 |
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Articles in Press |
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2025-06-10 04:08 |
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Publication Fee Transferred |
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2025-04-22 09:40 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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