Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	106692
Country	China

Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	MEX3A: A promising prognostic marker and therapeutic target in hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Xin-Le Yang and Xiao-Jun Yang
Funding Agency and Grant Number
Corresponding Author	Xiao-Jun Yang, Professor, Department of General Surgery, Gansu Provincial People’s Hospital, No. 199 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. yangxjmd@aliyun.com
Key Words	MEX3A; Hepatocellular carcinoma; Immune microenvironment; Cancer stem cells; Immunotherapy; Organoids
Core Tip	Ji et al’s study explored MEX3A’s role in hepatocellular carcinoma, showing its potential as a marker and target. It has limitations such as small sample size. New directions include studying its relations with immune microenvironment and cancer stem cells, such as analyzing the composition of immune cells and detecting the effect of knockdown of MEX3A on immunotherapy. Addressing them may improve hepatocellular carcinoma prognosis.
Citation	Yang XL, Yang XJ. MEX3A: A promising prognostic marker and therapeutic target in hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press

Received	2025-03-05 11:12
Peer-Review Started	2025-03-05 11:12
To Make the First Decision
Return for Revision	2025-03-21 07:29
Revised	2025-04-04 03:33
Second Decision	2025-04-21 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-21 06:47
Articles in Press	2025-04-21 06:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-05-06 10:50
Typeset the Manuscript

ISSN	1948-5204 (online)
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