Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	106995
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical efficacy of neoadjuvant chemotherapy combined with radical gastrectomy in elderly patients with advanced gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Liu-Liu Wei, Yue-Liang Lai, Kang-Hua Qiu, Xin He and Tao Yang
Funding Agency and Grant Number
Corresponding Author	Tao Yang, Department of Dermatology, First Affiliated Hospital of Gannan Medical University, No. 130 Zhangjiang North Avenue, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. danny20021068@126.com
Key Words	Gastric neoplasms; Tumor adjuvant therapy; Elderly people; Postoperative complications; Survival prognosis
Core Tip	Neoadjuvant chemotherapy combined with radical gastrectomy is a safe and effective treatment for elderly patients with advanced gastric cancer. Despite the increased risk of pulmonary complications, such as pleural effusion and pulmonary infection, postoperative recovery time and survival outcomes are similar to younger patients. Hematological and non-hematological complications related to chemotherapy are generally manageable. While age-related factors may affect chemotherapy tolerance, the combination therapy significantly improves surgical resectability and prognosis. Close monitoring of renal function and attention to pulmonary and cardiovascular issues are crucial for optimizing treatment outcomes in elderly gastric cancer patients.
Citation	Wei LL, Lai YL, Qiu KH, He X, Yang T. Clinical efficacy of neoadjuvant chemotherapy combined with radical gastrectomy in elderly patients with advanced gastric cancer. World J Gastrointest Surg 2025; In press

Received	2025-04-18 09:24
Peer-Review Started	2025-04-18 09:25
To Make the First Decision
Return for Revision	2025-05-14 11:12
Revised	2025-06-04 10:49
Second Decision	2025-07-11 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-11 07:04
Articles in Press	2025-07-11 07:04
Publication Fee Transferred	2025-06-07 01:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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