Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	107165
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Monogenic inflammatory bowel disease: An unfolding enigma
Manuscript Source	Invited Manuscript
All Author List	Upasana Ghosh and Arghya Samanta
Funding Agency and Grant Number
Corresponding Author	Arghya Samanta, Assistant Professor, Department of Pediatric Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. arghyasamanta29051989@gmail.com
Key Words	Whole exome sequencing; Primary immunodeficiency; Very early-onset inflammatory bowel disease; Monogenic inflammatory bowel disease; Inflammatory bowel disease
Core Tip	Monogenic inflammatory bowel disease (IBD) is an evolving entity in pediatric IBD. It constitutes a small but important fraction of pediatric IBD; understanding its pathogenesis and clinical manifestations is vital for evaluation and accurate management. This review discusses the etiologies, clinical manifestations, and therapeutic challenges in the management of monogenic IBD.
Citation	Ghosh U, Samanta A. Monogenic inflammatory bowel disease: An unfolding enigma. World J Clin Pediatr 2025; In press

Received	2025-03-17 08:14
Peer-Review Started	2025-03-17 08:14
To Make the First Decision
Return for Revision	2025-03-27 08:31
Revised	2025-04-10 09:08
Second Decision	2025-05-07 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-07 13:49
Articles in Press	2025-05-07 13:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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