Publication Name	World Journal of Clinical Oncology
Manuscript ID	107208
Country	United States

Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	GPR81 nuclear transportation is critical for cancer growth and progression in lung and other solid cancers
Manuscript Source	Unsolicited Manuscript
All Author List	LiBang Yang, Thomas Kono, Adam Gilbertsen, Yingming Li, Bo Sun, Blake A Jacobson, Sabine Karam, Scott M Dehm, Craig A Henke and Robert A Kratzke
Funding Agency and Grant Number
Corresponding Author	LiBang Yang, MD, PhD, Senior Researcher, Department of Medicine, University of Minnesota, 420 Delaware Street, Minneapolis, MN 55455, United States. yangx822@umn.edu
Key Words	Solid cancers; GPR81; Nuclear translocation; Proteomics; Chromatin immunoprecipitation sequencing; Ingenuity pathway analysis; Warburg effect; Self-renewal; Invasion
Core Tip	Lactate promotes GPR81 expression and nuclear transportation. where GPR81 interacts with nuclear proteins and regulates cancer cell function. Then targeting GPR81 and its nuclear transportation provides an opportunity to develop novel treatments targeting cancers.
Citation	Yang L, Kono T, Gilbertsen A, Li Y, Sun B, Jacobson BA, Karam S, Dehm SM, Henke CA, Kratzke RA. GPR81 nuclear transportation is critical for cancer growth and progression in lung and other solid cancers. World J Clin Oncol 2025; In press

Received	2025-03-18 12:42
Peer-Review Started	2025-03-18 12:43
To Make the First Decision
Return for Revision	2025-04-28 09:18
Revised	2025-05-19 19:50
Second Decision	2025-07-08 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-08 08:52
Articles in Press	2025-07-08 08:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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