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Publication Name World Journal of Hepatology
Manuscript ID 107223
Country United States
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Evolving therapeutic landscape of primary biliary cholangitis: A review
Manuscript Source Invited Manuscript
All Author List Natalie E Mitchell, Shu-Yen Chan, David Jerez Diaz, Nida Ansari, Junseo Lee and Patrick Twohig
Funding Agency and Grant Number
Corresponding Author Patrick Twohig, Assistant Professor, FRCPC, Department of Gastroenterology & Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14682, United States. patrick_twohig@urmc.rochester.edu
Key Words Primary biliary cholangitis; Ursodeoxycholic acid; Obeticholic acid; Fibrates; Peroxisome proliferator-activated receptor agonists
Core Tip Primary biliary cholangitis (PBC) is a chronic, progressive, cholestatic autoimmune liver disease predominantly affecting middle-aged women. Novel therapeutic strategies have emerged in recent years, providing promising treatment options for more refractory disease. This comprehensive review provides an overview of existing and new treatment therapies for PBC.
Citation Mitchell NE, Chan SY, Jerez Diaz D, Ansari N, Lee J, Twohig P. Evolving therapeutic landscape of primary biliary cholangitis: A review. World J Hepatol 2025; In press
Received
2025-03-19 13:23
Peer-Review Started
2025-03-24 00:09
To Make the First Decision
Return for Revision
2025-04-01 12:55
Revised
2025-04-23 11:33
Second Decision
2025-06-09 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-09 06:45
Articles in Press
2025-06-09 06:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com