Publication Name	World Journal of Gastroenterology
Manuscript ID	107260
Country	Serbia

Category	Immunology
Manuscript Type	Review
Article Title	Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets
Manuscript Source	Invited Manuscript
All Author List	Nevena M Gajovic, Ivan P Jovanovic, Miodrag V Jocic, Bojan Stojanovic, Irfan F Corovic, Nevena Todorovic, Bojana J Simovic Markovic and Amedeo Amedei
Funding Agency and Grant Number
Corresponding Author	Bojana J Simovic Markovic, Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovic 69, Kragujevac 34000, Serbia. bojana.simovic@gmail.com
Key Words	Hepatocellular carcinoma; Liver cancer; Galectins; Galectin-3; Galectin-1; Immunopathogenesis; Biomarkers
Core Tip	Hepatocellular carcinoma remains a significant global health challenge characterized by complex molecular and immune-mediated mechanisms. This review provides an in-depth overview of key pathways driving hepatocellular carcinoma pathogenesis, with particular emphasis on the emerging roles of galectins-especially galectin-1 and galectin-3. Their involvement in inflammation, immune regulation, and tumor progression underscores their potential as valuable biomarkers and promising targets for personalized therapeutic strategies.
Citation	<p>Gajovic NM, Jovanovic IP, Jocic MV, Stojanovic B, Corovic IF, Todorovic N, Simovic Markovic BJ, Amedei A. Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets. <i>World J Gastroenterol</i> 2025; 31(25): 107260</p>

Received	2025-03-19 10:27
Peer-Review Started	2025-03-19 10:27
To Make the First Decision
Return for Revision	2025-04-08 07:06
Revised	2025-04-19 01:26
Second Decision	2025-06-12 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-12 07:27
Articles in Press	2025-06-12 07:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-06-15 23:27
Typeset the Manuscript	2025-06-28 09:02

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com