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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 107364
Country South Korea
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Risk of hepatocellular carcinoma according to body mass index and waist circumference in nonalcoholic fatty liver disease
Manuscript Source Unsolicited Manuscript
All Author List Han Na Jung, Ji Hye Heo, Eun Roh, Bum Jun Kim, Minwoo Lee, Jwa-Kyung Kim, Joo-Hee Kim, Boram Han, Kyung-Do Han, Jun Goo Kang, Seong Jin Lee and Sung-Hee Ihm
Funding Agency and Grant Number
Corresponding Author Jun Goo Kang, Department of Internal Medicine, Hallym University College of Medicine, No. 22 Gwanpyeong-ro 170beon-gil, Dongan-gu, Chuncheon-si 24252, Gangwon-do, South Korea. kjg0804@empas.com
Key Words Hepatocellular carcinoma; Adiposity; Body mass index; Waist circumference; Nonalcoholic fatty liver disease
Core Tip While the risk of hepatocellular carcinoma (HCC) increases with body mass index and waist circumference (WC) in the general population, the risk in nonalcoholic fatty liver disease (NAFLD) is unknown. This population-based study of people with NAFLD demonstrated a U-shaped association of body mass index and WC with HCC, with the highest risk in the underweight and lowest WC groups. These findings suggest that surveillance for incident HCC is necessary in populations with NAFLD, irrespective of obesity, with particular attention to individuals with low adiposity.
Citation Jung HN, Heo JH, Roh E, Kim BJ, Lee M, Kim JK, Kim JH, Han B, Han KD, Kang JG, Lee SJ, Ihm SH. Risk of hepatocellular carcinoma according to body mass index and waist circumference in nonalcoholic fatty liver disease. World J Gastrointest Oncol 2025; In press
Received
2025-03-21 16:05
Peer-Review Started
2025-03-21 16:05
To Make the First Decision
Return for Revision
2025-04-02 11:01
Revised
2025-04-03 11:43
Second Decision
2025-04-17 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-17 08:38
Articles in Press
2025-04-17 08:38
Publication Fee Transferred
2025-04-08 09:09
Edit the Manuscript by Language Editor
2025-04-23 16:44
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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