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7/7/2025 8:24:10 AM | Browse: 9 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 107400
Country Türkiye
Category Cell Biology
Manuscript Type Minireviews
Article Title Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review
Manuscript Source Invited Manuscript
All Author List Demet Kacaroglu and Nilgun Gurbuz
Funding Agency and Grant Number
Corresponding Author Nilgun Gurbuz, PhD, Professor, Department of Medical Biology, Faculty of Medicine, Suleyman Demirel University, Çünür, Doğu Yerleşkesi, 32200 Merkez/Isparta, Isparta 32260, Türkiye. nilgungurbuz@sdu.edu.tr
Key Words Exosomes; Pancreatic cancer; Mesenchymal stem cell exosomes; Macrophage exosomes; Small extracellular vesicles
Core Tip Pancreatic cancer has high metastatic potential and low survival rates due to its dense desmoplastic microenvironment, which limits drug delivery. Exosomes, with their low immunogenicity and targeting ability, are promising therapeutic carriers. Mesenchymal stem cell- and macrophage-derived exosomes show potential in pancreatic cancer treatment. This review compares their effects, summarizing in vitro, in vivo, and clinical studies while highlighting their advantages and disadvantages.
Citation Kacaroglu D, Gurbuz N. Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review. World J Stem Cells 2025; In press
Received
2025-03-24 05:53
Peer-Review Started
2025-03-25 01:36
To Make the First Decision
Return for Revision
2025-04-17 10:56
Revised
2025-04-27 11:38
Second Decision
2025-07-04 02:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-07 08:24
Articles in Press
2025-07-07 08:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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