Publication Name	World Journal of Stem Cells
Manuscript ID	107400
Country	Türkiye

Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review
Manuscript Source	Invited Manuscript
All Author List	Demet Kacaroglu and Nilgun Gurbuz
Funding Agency and Grant Number
Corresponding Author	Nilgun Gurbuz, PhD, Professor, Department of Medical Biology, Faculty of Medicine, Suleyman Demirel University, Çünür, Doğu Yerleşkesi, 32200 Merkez/Isparta, Isparta 32260, Türkiye. nilgungurbuz@sdu.edu.tr
Key Words	Exosomes; Pancreatic cancer; Mesenchymal stem cell exosomes; Macrophage exosomes; Small extracellular vesicles
Core Tip	Pancreatic cancer has high metastatic potential and low survival rates due to its dense desmoplastic microenvironment, which limits drug delivery. Exosomes, with their low immunogenicity and targeting ability, are promising therapeutic carriers. Mesenchymal stem cell- and macrophage-derived exosomes show potential in pancreatic cancer treatment. This review compares their effects, summarizing in vitro, in vivo, and clinical studies while highlighting their advantages and disadvantages.
Citation	Kacaroglu D, Gurbuz N. Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review. World J Stem Cells 2025; In press

Received	2025-03-24 05:53
Peer-Review Started	2025-03-25 01:36
To Make the First Decision
Return for Revision	2025-04-17 10:56
Revised	2025-04-27 11:38
Second Decision	2025-07-04 02:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-07 08:24
Articles in Press	2025-07-07 08:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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