Publication Name	World Journal of Diabetes
Manuscript ID	107517
Country	India

Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Type 2 diabetes mellitus: Isn’t it time to update the terminology?
Manuscript Source	Invited Manuscript
All Author List	Arkiath Veettil Raveendran
Funding Agency and Grant Number
Corresponding Author	Arkiath Veettil Raveendran, Chief Physician, FRCP, MD, Department of Internal Medicine, Government Medical College, Mavoor Road, Kozhikode 673010, Kerala, India. raveendranav@yahoo.co.in
Key Words	Diabetes mellitus; Adiposity; Obesity; Personal fat threshold; Personal organ-specific fat threshold; Adiposity induced metabolic dysfunction associated diseases; Metabolic dysfunction associated hyperglycemic disease
Core Tip	Recent research has led to a paradigm shift in the treatment approach for type 2 diabetes mellitus (T2DM). The “twin cycle hypothesis” and evidence supporting diabetes remission have shown that the condition results from excess fat accumulation above the personal fat threshold. When excess fat deposition leads to organ dysfunction, we term it as adiposity-induced metabolic dysfunction associated disease. T2DM is a part of the spectrum of diseases caused by excess fat accumulation. Hence, it is the need of the hour to update the terminology and we propose a new terminology for T2DM. The proposed terminology is more reflective of the multifaceted nature of the disease, reshapes the management protocols and helps in earlier diagnosis and treatment.
Citation	Raveendran AV. Type 2 diabetes mellitus: Isn’t it time to update the terminology? World J Diabetes 2025; In press

Received	2025-03-25 06:52
Peer-Review Started	2025-03-31 00:18
To Make the First Decision
Return for Revision	2025-04-14 07:08
Revised	2025-05-20 01:24
Second Decision	2025-08-13 05:13
Accepted by Journal Editor-in-Chief	2025-08-13 06:00
Accepted by Executive Editor-in-Chief	2025-08-19 08:04
Articles in Press	2025-08-19 08:04
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ISSN	1948-9358 (online)
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