Publication Name	World Journal of Critical Care Medicine
Manuscript ID	107570
Country	United States

Category	Neurosciences
Manuscript Type	Meta-Analysis
Article Title	Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Andrea Loggini, Amber Schwertman, Jonatan Hornik, Karam Dallow and Alejandro Hornik
Funding Agency and Grant Number
Corresponding Author	Andrea Loggini, Brain and Spine Institute, Southern Illinois Healthcare, 405 W Jackson Street, Carbondale, IL 62901, United States. andrea.loggini@sih.net
Key Words	Telemedicine; Acute ischemic stroke; Door-to-needle; Meta-analysis
Core Tip	In this meta-analysis, we compared telemedicine technology to in-person evaluation for the treatment of acute ischemic stroke, highlighting the differences in door-to-needle time (DTN) between the two modalities, and the impact of them on outcomes. The literature suggests that the stroke metric, in terms of DTN, is longer by telemedicine modality of evaluation. However, this difference does not translate in differences in safety and outcomes.
Citation	Loggini A, Schwertman A, Hornik J, Dallow K, Hornik A. Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: a meta-analysis. World J Crit Care Med 2025; In press

Received	2025-03-26 04:06
Peer-Review Started	2025-03-26 04:06
To Make the First Decision
Return for Revision	2025-04-01 04:33
Revised	2025-04-11 17:15
Second Decision	2025-05-27 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-27 10:43
Articles in Press	2025-05-27 10:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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