Publication Name	World Journal of Gastroenterology
Manuscript ID	107661
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Cardiometabolic diseases in patients with inflammatory bowel disease: An evidence-based review
Manuscript Source	Invited Manuscript
All Author List	Krishneel Dutt, Abhinav Vasudevan, Alexander Hodge, Tuan L Nguyen and Ashish R Srinivasan
Funding Agency and Grant Number
Corresponding Author	Ashish R Srinivasan, Associate Professor, FRACP, PhD, Department of Gastroenterology and Hepatology, Eastern Health, 8 Arnold Street, Box Hill 3128, Victoria, Australia. ashish.srinivasan1@gmail.com
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Metabolic syndrome; Obesity; Cardiovascular disease; Stroke; Metabolic liver disease; Cardiometabolic diseases; Gastrointestinal inflammation
Core Tip	Emerging evidence supports a biological link between chronic gastrointestinal inflammation and the development of cardiometabolic diseases later in life. This is particularly relevant for inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis, which are chronic immune-mediated disorders of the gastrointestinal tract. Observational studies indicate that IBD may increase the risk of cardiometabolic diseases. However, the role of uncontrolled intestinal inflammation in exacerbating this risk-and whether treat-to-target strategies aimed at controlling inflammation in IBD could mitigate these comorbidities-remains unclear. This review provides clinicians with an evidence-based summary of the associations between IBD and cardiometabolic diseases.
Citation	Dutt K, Vasudevan A, Hodge A, Nguyen TL, Srinivasan AR. Cardiometabolic diseases in patients with inflammatory bowel disease: An evidence-based review. World J Gastroenterol 2025; In press

Received	2025-03-28 05:59
Peer-Review Started	2025-03-28 05:59
To Make the First Decision
Return for Revision	2025-04-17 00:58
Revised	2025-04-26 05:44
Second Decision	2025-06-09 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-09 06:56
Articles in Press	2025-06-09 06:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com