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Articles in Press
8/22/2025 7:39:23 AM | Browse: 134 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Critical flicker frequency improves after alcohol detoxification and is associated with liver stiffness
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Omar Elshaarawy, Shuai Lan, Johannes Mueller and Sebastian Mueller |
| Funding Agency and Grant Number |
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| Corresponding Author |
Sebastian Mueller, PhD, Professor, Center for Alcohol Research, University of Heidelberg, In Neuenheimer Feld 350, Heidelberg 69120, Baden-Württemberg, Germany. sebastian.mueller@urz.uni-heidelberg.de |
| Key Words |
Critical flicker frequency; Hepatic encephalopathy; Alcohol-related liver disease; Fibrosis; Cirrhosis; Transient elastography; Liver stiffness |
| Core Tip |
This study demonstrates that critical flicker frequency (CFF), a non-invasive marker of neurocognitive function, significantly improves following alcohol detoxification in patients with alcohol-related liver disease (ALD). CFF was reduced in ALD patients and correlated with liver stiffness, particularly post-detoxification, highlighting its utility in detecting minimal hepatic encephalopathy. These findings underscore CFF’s value in assessing alcohol-related neurotoxicity and monitoring therapeutic response, supporting its integration into routine evaluation of patients with ALD and cirrhosis. |
| Citation |
Elshaarawy O, Lan S, Mueller J, Mueller S. Critical flicker frequency improves after alcohol detoxification and is associated with liver stiffness. World J Gastroenterol 2025; 31(36): 107703 |
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Received |
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2025-04-07 02:50 |
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Peer-Review Started |
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2025-04-07 02:50 |
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First Decision by Editorial Office Director |
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2025-04-20 03:42 |
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Return for Revision |
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2025-04-20 03:42 |
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Revised |
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2025-05-18 14:50 |
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Publication Fee Transferred |
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2025-06-02 14:09 |
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Second Decision by Editor |
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2025-08-22 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-22 07:39 |
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Articles in Press |
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2025-08-22 07:39 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-11 06:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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