Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	107919
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Noninvasive prediction of Ki-67 expression in pancreatic cancer via contrast-enhanced ultrasound quantitative parameters: A diagnostic model study
Manuscript Source	Unsolicited Manuscript
All Author List	Zi-Yi Yang, Wei-Na Wan, Lei Zhao, Si-Nong Li, Zhe Liu and Liang Sang
Funding Agency and Grant Number	Funding Agency Grant Number Liaoning Province Science and Technology Plan Joint Program No. 2024JH2/102600310
Corresponding Author	Liang Sang, Department of Ultrasonography, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110001, Liaoning Province, China. 20091213@cmu.edu.cn
Key Words	Contrast-enhanced ultrasound; Pancreatic cancer; Quantitative analysis; Ki-67 index; Pathological differentiation degree
Core Tip	This study systematically integrates contrast-enhanced ultrasound quantitative parameters with pathological markers (Ki-67 index and tumor grade) in pancreatic cancer for the first time. By combining ultrasonography, tumor pathology, and statistical methods, it provides a noninvasive approach to assess tumor proliferation and aggressiveness. The findings may enable more precise treatment decisions (e.g., surgery, chemotherapy, or targeted therapy), potentially improving clinical outcomes.
Citation	Yang ZY, Wan WN, Zhao L, Li SN, Liu Z, Sang L. Noninvasive prediction of Ki-67 expression in pancreatic cancer via contrast-enhanced ultrasound quantitative parameters: A diagnostic model study. World J Gastrointest Oncol 2025; In press

Received	2025-04-01 09:09
Peer-Review Started	2025-04-01 09:09
To Make the First Decision
Return for Revision	2025-04-16 09:31
Revised	2025-04-27 06:05
Second Decision	2025-05-21 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-21 07:02
Articles in Press	2025-05-21 07:02
Publication Fee Transferred	2025-05-01 06:44
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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