Publication Name	World Journal of Critical Care Medicine
Manuscript ID	108062
Country	Brazil

Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Physiotherapy approaches for pain control in patients who are critically ill
Manuscript Source	Invited Manuscript
All Author List	Ana Claudia Ometto, Gustavo Brasil Marcelino, Gabriella Cristina Nogueira Pereira, Felipe Farah Pinheiro Rodrigues, Raquel Afonso Caserta Eid and Arnaldo Alves da Silva
Funding Agency and Grant Number
Corresponding Author	Arnaldo Alves da Silva, MD, PhD, Professor, Senior Researcher, Department of Critical Care, Hospital Israelita Albert Einstein, Department of Critical Care, Hospital Israelita Albert Einstein, São Paulo, Brazil. renalmater@gmail.com, Sao Paulo 05652-900, SP, Brazil. renalmater@gmail.com
Key Words	Pain; Critically ill patients; Intensive care unit; Physiotherapy; Early mobilization; Nonpharmacological interventions; Patient comfort; Rehabilitation; Mechanical ventilation; Sedation reduction
Core Tip	Physiotherapy interventions offer effective nonpharmacological approaches to pain management in intensive care unit patients, potentially reducing reliance on opioids and their associated complications. This review highlights six evidence-based modalities-early mobilization, positioning, manual therapy, thermotherapy, transcutaneous electrical nerve stimulation, and photobiomodulation-that can complement conventional analgesic strategies. These interventions demonstrate efficacy in reducing pain intensity while improving patient comfort through multiple physiological mechanisms, presenting viable options for comprehensive pain management protocols in critical care settings.
Citation	Ometto AC, Marcelino GB, Nogueira Pereira GC, Pinheiro Rodrigues FF, Caserta Eid RA, da Silva AA. Physiotherapy approaches for pain control in patients who are critically ill. World J Crit Care Med 2025; In press

Received	2025-04-09 00:53
Peer-Review Started	2025-04-09 00:53
To Make the First Decision
Return for Revision	2025-04-27 01:56
Revised	2025-08-05 21:31
Second Decision	2025-11-17 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-17 08:35
Articles in Press	2025-11-17 08:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com