Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	108238
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Different titration protocols in pain management after radical gastrectomy for gastric cancer patients
Manuscript Source	Unsolicited Manuscript
All Author List	Bin-Bin Chen, Wei Tu, Ai-Dan Xia, Miao-Yong Zhu and Zi-Jie Wang
Funding Agency and Grant Number	Funding Agency Grant Number Wenzhou Science and Technology Bureau Y20220877
Corresponding Author	Zi-Jie Wang, Department of Tumor Center, Lishui Central Hospital, No. 289 Kuocang Road, Liandu District, Lishui 323020, Zhejiang Province, China. wzj202508@163.com
Key Words	Radical gastrectomy; Postoperative pain management; Titration regimen; Efficacy; Enhanced recovery after surgery
Core Tip	This study compared 12-hour and 24-hour analgesic titration regimens in postoperative pain management after radical gastrectomy for gastric cancer. Results showed that the 12-hour protocol significantly reduced pain intensity, analgesic consumption, and adverse effects, while improving patient satisfaction and recovery outcomes. The findings support the adoption of more frequent titration strategies within enhanced recovery after surgery protocols to optimize early postoperative pain control, minimize complications, and accelerate recovery. This study provides practical evidence for refining analgesic management and developing individualized postoperative care pathways for patients undergoing major abdominal surgery.
Citation	<p>Chen BB, Tu W, Xia AD, Zhu MY, Wang ZJ. Different titration protocols in pain management after radical gastrectomy for gastric cancer patients. <i>World J Gastrointest Oncol</i> 2025; 17(8): 108238</p>

Received	2025-05-14 08:49
Peer-Review Started	2025-05-14 08:49
To Make the First Decision
Return for Revision	2025-06-05 06:17
Revised	2025-06-15 13:21
Second Decision	2025-07-16 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-16 08:47
Articles in Press	2025-07-16 08:47
Publication Fee Transferred	2025-06-17 07:13
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-08-01 01:31

ISSN	1948-5204 (online)
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