Publication Name	World Journal of Gastroenterology
Manuscript ID	108508
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Application of artificial intelligence in portal hypertension and esophagogastric varices
Manuscript Source	Invited Manuscript
All Author List	Qing-Chen Wang, Jian Jiao and Chun-Qing Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 81970533 Natural Science Foundation of Shandong Province No. ZR2022ZD21
Corresponding Author	Chun-Qing Zhang, MD, PhD, Professor, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Weiqi Road, Jinan 250000, Shandong Province, China. zhangchunqing_sdu@163.com
Key Words	Cirrhosis; Portal hypertension; Esophagogastric variceal; Artificial intelligence; Diagnosis; Management
Core Tip	This review highlights the latest progress of artificial intelligence (AI) in the diagnosis and treatment of portal hypertension and esophagogastric varices. It emphasizes AI’s potential in early non-invasive diagnosis, risk prediction, and treatment optimization. Key points include the application of machine learning and deep learning in analyzing medical imaging and clinical data to improve diagnostic accuracy and personalized treatment. The review also discusses challenges in AI implementation, such as data quality, model interpretability, and regulatory requirements, and suggests future research directions focusing on enhancing AI’s role in clinical practice.
Citation	Wang QC, Jiao J, Zhang CQ. Application of artificial intelligence in portal hypertension and esophagogastric varices. World J Gastroenterol 2025; In press

Received	2025-04-16 06:38
Peer-Review Started	2025-04-16 06:38
To Make the First Decision
Return for Revision	2025-04-23 23:52
Revised	2025-05-07 10:28
Second Decision	2025-06-09 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-09 06:05
Articles in Press	2025-06-09 06:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com