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Publication Name World Journal of Clinical Cases
Manuscript ID 108566
Country Pakistan
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Ileocecal basidiobolomycosis mimicking malignancy successfully treated without surgery: A case report
Manuscript Source Invited Manuscript
All Author List Mohammed Saud Alsulaimi, Muhammed Yousuf Memon, Iman M Alyabary, Eman Almotairi, Tareq Sulaiman, Amal N Shamsan and Muhammed Mubarak
Funding Agency and Grant Number
Corresponding Author Muhammed Mubarak, Department of Histopathology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Key Words Basidiobolomycosis, Gastrointestinal basidiobolomycosis diagnosis, endoscopic biopsy, Splendore-Hoeppli phenomenon, Voriconazole, Posaconazole, Hepatotoxicity; Case report
Core Tip Gastrointestinal basidiobolomycosis (GIB) is a rare but potentially fatal fungal infection affecting immunocompetent individuals, often mimicking malignancy. This case highlights a 32-year-old Saudi male presenting with right lower quadrant abdominal pain and an ileocecal mass, initially suspected as colon cancer. Colonoscopy and histopathology confirmed GIB, revealing fungal hyphae, eosinophilic infiltration, and granulomatous inflammation. Voriconazole therapy induced hepatotoxicity, necessitating a switch to posaconazole. The patient achieved full clinical and radiological resolution after four months. Early recognition and targeted antifungal therapy are essential for favorable outcomes. This case underscores the importance of considering GIB in the differential diagnoses of abdominal masses in endemic regions.
Citation Alsulaimi MS, Memon MY, Alyabary IM, Almotairi E, Sulaiman T, Shamsan AN, Mubarak M. Ileocecal basidiobolomycosis mimicking malignancy successfully treated without surgery: A case report. World J Clin Cases 2025; In press
Received
2025-04-17 11:33
Peer-Review Started
2025-04-17 11:34
To Make the First Decision
Return for Revision
2025-06-10 07:04
Revised
2025-07-05 06:12
Second Decision
2025-08-14 03:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-15 03:02
Articles in Press
2025-08-15 03:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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