Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	108579
Country	China

Category	Medicine, General & Internal
Manuscript Type	Observational Study
Article Title	Outcomes of iodine-125 seed strips combined with double self-expandable metallic stent for Bismuth type III and IV malignant biliary obstruction
Manuscript Source	Unsolicited Manuscript
All Author List	Chuan-Guo Zhou, Yong Zhang, Hui Li, Ke-Yun Liu, Xiang-Yu Yang and Kun Gao
Funding Agency and Grant Number
Corresponding Author	Chuan-Guo Zhou, MD, Department of Interventional Radiology, Beijing Chaoyang Hospital, The Affiliated Hospital of Capital Medical University, No. 8 Gongren Tiyuchang Nan Road, Chaoyang District, Beijing 100020, China. zhoucg3949_cn@sina.com
Key Words	Iodine-125 seeds; Self-expandable metallic stent; Hilar malignant biliary obstruction; Hilar cholangiocarcinoma; Case series study
Core Tip	This study explores the innovative use of iodine-125 seed strips combined with double self-expandable metallic stent for treating Bismuth type III and IV hilar malignant biliary obstruction. In a retrospective analysis of 17 patients from April 2017 to December 2022, we achieved a technical success rate of 94.1% and a clinical success rate of 100%. The median overall survival was 189 days, with stent patency lasting an average of 154 days. No serious complications were reported, indicating that this combination therapy is a safe and effective treatment option for these patients.
Citation	Zhou CG, Zhang Y, Li H, Liu KY, Yang XY, Gao K. Outcomes of iodine-125 seed strips combined with double self-expandable metallic stent for Bismuth type III and IV malignant biliary obstruction. World J Gastrointest Surg 2025; In press

Received	2025-04-22 06:58
Peer-Review Started	2025-04-22 06:58
To Make the First Decision
Return for Revision	2025-05-16 17:04
Revised	2025-05-30 02:20
Second Decision	2025-06-30 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-30 07:56
Articles in Press	2025-06-30 07:56
Publication Fee Transferred	2025-06-01 09:52
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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