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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 108679
Country China
Category Oncology
Manuscript Type Retrospective Study
Article Title Value of intravoxel incoherent motion and diffusion kurtosis imaging to differentiate hepatocellular carcinoma and intrahepatic cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Shan-Mei Li, Meng-Wei Feng, Guang-Hai Ji, Xiao-Peng Song, Wei Mao, Tao Zhou, Xiao-Fang Guo, Zi-Long Yuan and Yu-Lin Liu
Funding Agency and Grant Number
Funding Agency Grant Number
Chutian Talents of Hubei No. CTYC001
Talent Project of Hubei Cancer Hospital No. 2025HBCHLHRC001
Clinical Medical Science and Technology of Jinan No. 202134053
Corresponding Author Zi-Long Yuan, Associate Professor, Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 116 Zhuodaoquan South Road, Hongshan District, Wuhan 430079, Hubei Province, China. yuanzilong0213@126.com
Key Words Hepatocellular carcinoma; Magnetic resonance imaging; Intrahepatic cholangiocarcinoma; Intravoxel incoherent motion; Diffusion kurtosis imaging
Core Tip This study employed intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) for liver cancer and intrahepatic cholangiocarcinoma. The findings suggest that the parameters shifted apparent diffusion coefficient (SADC) and pure diffusion coefficient from IVIM and mean kurtosis coefficient and mean diffusion coefficient from DKI, can differentiate between the two tumor types. Among them SADC demonstrated the highest diagnostic value, and particularly when used in the joint model. The innovation of this lies in the application of the DKI sequence for the first time and analyze its value.
Citation Li SM, Feng MW, Ji GH, Song XP, Mao W, Zhou T, Guo XF, Yuan ZL, Liu YL. Value of intravoxel incoherent motion and diffusion kurtosis imaging to differentiate hepatocellular carcinoma and intrahepatic cholangiocarcinoma. World J Gastrointest Oncol 2025; In press
Received
2025-04-21 05:26
Peer-Review Started
2025-04-21 05:27
To Make the First Decision
Return for Revision
2025-05-22 10:09
Revised
2025-05-27 07:32
Second Decision
2025-06-30 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-30 09:08
Articles in Press
2025-06-30 09:08
Publication Fee Transferred
2025-05-28 14:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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