Publication Name	World Journal of Experimental Medicine
Manuscript ID	108702
Country	India

Category	Ophthalmology
Manuscript Type	Prospective Study
Article Title	Ganglion cell complex and retinal nerve fiber layer thickness in predicting visual outcome in brain tumors after surgery
Manuscript Source	Invited Manuscript
All Author List	Sucheta Parija, Koyel Chakraborty, Rabi Narayan Sahu, Bhagabat Nayak and Ravikumar Subraya Rathod
Funding Agency and Grant Number
Corresponding Author	Sucheta Parija, Head, Professor, Department of Ophthalmology, All India Institute Of Medical Sciences, Dept of Ophthalmology, AIIMS Bhubaneswar, Patrapada, Bhubaneswar, Bhubaneshwar 751019, Odisha, India. ophthal_sucheta@aiimsbhubaneswar.edu.in
Key Words	Ganglion cell complex; Brain tumors; Retinal nerve fiber layer; Optical coherence tomography; Visual prognosis; Visual field; Chiasmatic compression
Core Tip	This study was conducted among perichiasmatic brain tumor patients in which optical coherence tomography (OCT) was used to detect ganglion cell complex (GCC) and retinal nerve fibre layer (RNFL) damage as well as prognosticate visual outcome. A positive correlation was noted between GCC thickness, visual acuity and field defect at six months postoperatively. The predictors of blindness were reduced baseline GCC and RNFL thickness. A minimum cut-off value predicting preservation of vision was a RNFL thickness of 73 µm and a GCC thickness of 58 µm. Hence, it can guide early intervention by a neurosurgeon for vision preservation.
Citation	Parija S, Chakraborty K, Sahu RN, Nayak B, Rathod RS. Ganglion cell complex and retinal nerve fiber layer thickness in predicting visual outcome in brain tumors after surgery. World J Exp Med 2025; In press

Received	2025-04-22 06:08
Peer-Review Started	2025-04-23 00:41
To Make the First Decision
Return for Revision	2025-05-27 10:45
Revised	2025-06-10 10:27
Second Decision	2025-09-16 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-16 09:27
Articles in Press	2025-09-16 09:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-315x (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com