Publication Name	World Journal of Cardiology
Manuscript ID	109044
Country	China

Category	Hematology
Manuscript Type	Retrospective Study
Article Title	Risk factors and predictive model for mortality in acute myocardial infarction with ventricular septal rupture at high altitude
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Hong Zhang, Zhi-Fu Cen, Qian Qiao, Xue-Rui Ye, Lu Cheng, Gui-Qin Liu, Yi Liu, Xing-Qiang Zhang, Xian-Feng Pan, Hao-Ling Zhang and Jing-Jing Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Department of Yunnan Province - Kunming Medical University, Kunming Medical joint special project - surface project No.202401AY070001-164 Yunnan Provincial Department of Science and Technology Science and Technology Plan Project - Key Research and Development Program No.202103AC100004 Yunnan Provincial Clinical Research Center Cardiovascular Diseases - New Technology Research for Development Project for Diagnosis and Treatment Cardiovascular Diseases No.202102AA310002 Yunnan Provincial Department of Science and Technology Science and Technology Plan Project—Major Science and Technology Special Projects No.202405AJ310003
Corresponding Author	Jing-Jing Zhang, Assistant Professor, Department of Cardiovascular Medicine, Fuwai Yunnan Hospital, Chinese Academy Medical Sciences, No. 88, East Kunming Road, Kunming 650000, Yunnan Province, China. zhangjingjing1@kmmu.edu.cn
Key Words	High-altitude regions; Acute myocardial infarction complicated by ventricular septal rupture; Mortality risk factors; Nomogram predictive model
Core Tip	This study identifies key clinical factors—age, uric acid, interleukin-6, and hemoglobin—as significant predictors of 30-day mortality in acute myocardial infarction complicated by ventricular septal rupture at high altitudes. A nomogram model developed from these risk factors demonstrates excellent predictive power, offering a valuable tool for early mortality risk assessment and intervention in high-risk populations.
Citation	Zhang LH, Cen ZF, Qiao Q, Ye XR, Cheng L, Liu GQ, Liu Y, Zhang XQ, Pan XF, Zhang HL, Zhang JJ. Risk Factors and Predictive Model for Mortality in Acute Myocardial Infarction with Ventricular Septal Rupture at High Altitude. World J Cardiol 2025; In press

Received	2025-04-29 04:20
Peer-Review Started	2025-04-29 04:21
To Make the First Decision
Return for Revision	2025-05-17 08:47
Revised	2025-05-29 10:52
Second Decision	2025-06-30 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-30 08:11
Articles in Press	2025-06-30 08:11
Publication Fee Transferred	2025-06-03 05:51
Edit the Manuscript by Language Editor	2025-07-01 03:20
Typeset the Manuscript

ISSN	1949-8462 (online)
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