Publication Name	World Journal of Gastroenterology
Manuscript ID	109090
Country	Malaysia

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gut-liver axis in diabetes: Mechanisms and therapeutic opportunities
Manuscript Source	Invited Manuscript
All Author List	Mona Mohamed Ibrahim Abdalla
Funding Agency and Grant Number
Corresponding Author	Mona Mohamed Ibrahim Abdalla, MD, PhD, Department of Human Biology, School of Medicine, International Medical University, No. 126 Jln Jalil Perkasa 19, Bukit Jalil 57000, Kuala Lumpur, Malaysia. monamohamed@imu.edu.my
Key Words	Diabetes; Microbiota; Diabetes management; Gut-liver axis; Anti-inflammatory; Intestinal permeability; Metabolic homeostasis
Core Tip	Disruption of the gut-liver axis plays a critical role in the pathophysiology of diabetes by linking gut microbiota alterations, intestinal barrier dysfunction, and inflammatory pathways to hepatic insulin resistance and impaired glucose metabolism. Understanding these mechanisms opens new therapeutic opportunities, including microbiota modulation, gut barrier reinforcement, and targeted anti-inflammatory strategies. These approaches have the potential to significantly improve diabetes management and metabolic outcomes.
Citation	<p>Abdalla MMI. Gut-liver axis in diabetes: Mechanisms and therapeutic opportunities. <i>World J Gastroenterol</i> 2025; 31(29): 109090</p>

Received	2025-04-29 02:42
Peer-Review Started	2025-04-29 02:42
To Make the First Decision
Return for Revision	2025-05-20 19:27
Revised	2025-06-03 16:10
Second Decision	2025-07-08 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-08 03:25
Articles in Press	2025-07-08 03:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-27 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
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